Acotiamida

Acotiamida
Nombre IUPAC
	N-{2-[bis(1-methylethyl)amino]ethyl}-2-{[(2-hydroxy-4,5-dimethoxyphenyl)carbonyl]amino}-1,3-thiazole-4-carboxamide
General
Fórmula estructural
Fórmula molecular	C21H30N4O5S
Identificadores
Número CAS	185106-16-5
ChEBI	34523
ChEMBL	CHEMBL2107723
ChemSpider	4445505
DrugBank	12482
PubChem	5282338
UNII	D42OWK5383
KEGG	C14127
	SMILES O=C(Nc1nc(C(=O)NCCN(C(C)C)C(C)C)cs1)c2cc(OC)c(OC)cc2O
	InChI InChI=1S/C21H30N4O5S/c1-12(2)25(13(3)4)8-7-22-20(28)15-11-31-21(23-15)24-19(27)14-9-17(29-5)18(30-6)10-16(14)26/h9-13,26H,7-8H2,1-6H3,(H,22,28)(H,23,24,27); Key: TWHZNAUBXFZMCA-UHFFFAOYSA-N
Propiedades físicas
Masa molar	450.55 g/mol g/mol
	Valores en el SI y en condiciones estándar; (25 ℃ y 1 atm), salvo que se indique lo contrario.
	[editar datos en Wikidata]

Acotiamida (YM-443, Z-338) es un experimental inhibidor de la colinesterasa^[2]

Referencias[editar]

↑ Número CAS
↑ Matsueda K, Hongo M, Tack J, Aoki H, Saito Y, Kato H (enero de 2010). «Clinical trial: dose-dependent therapeutic efficacy of acotiamide hydrochloride (Z-338) in patients with functional dyspepsia - 100 mg t.i.d. is an optimal dosage». Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society 22 (6): 618-e173. PMID 20059698. doi:10.1111/j.1365-2982.2009.01449.x.